Interstitial cystitis
Interstitial cystitis (IC), also known as painful bladder syndrome, is a chronic condition characterized by bladder pain, pressure, and frequent, urgent urination. The exact cause is unknown, but it may involve bladder wall inflammation or damage, and it can be triggered by infections, trauma, or certain foods. Treatments focus on symptom relief and may include lifestyle changes, bladder training, oral medications (such as antihistamines or pain relievers), and bladder instillations. In severe cases, physical therapy, nerve stimulation, or surgery may be considered. Managing IC typically requires a multidisciplinary approach to improve quality of life.

Interstitial cystitis (IC), also known as painful bladder syndrome, is a chronic condition characterized by bladder pain, pressure, and frequent, urgent urination. The exact cause is unknown, but it may involve bladder wall inflammation or damage, and it can be triggered by infections, trauma, or certain foods. Treatments focus on symptom relief and may include lifestyle changes, bladder training, oral medications (such as antihistamines or pain relievers), and bladder instillations. In severe cases, physical therapy, nerve stimulation, or surgery may be considered. Managing IC typically requires a multidisciplinary approach to improve quality of life.
Treatment
1. Lifestyle and Behavioral Modifications:
Dietary Adjustments: Identifying and avoiding foods and beverages that trigger symptom flare-ups can be beneficial. Keeping a food diary may help pinpoint specific irritants.
Stress Management: Engaging in relaxation techniques and activities that reduce stress can help manage symptoms, as stress may exacerbate
Bladder Training: Implementing bladder training techniques can help increase bladder capacity and reduce urgency and frequency.
2. Physical Therapies:
Pelvic Floor Physiotherapy: Working with a specialist to relax and strengthen pelvic floor muscles can alleviate pain and improve bladder function.
3. Medications:
Oral Medications:
Pain Relievers: Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen sodium, may help reduce pain.
Antidepressants: Tricyclic antidepressants like amitriptyline can help relax the bladder and block pain.
Antihistamines: Medications like hydroxyzine may reduce urinary urgency and frequency.
Bladder Instillations: Directly instilling medications into the bladder can provide relief. A combination of medications, including lidocaine, heparin, and sodium bicarbonate, is believed to help repair the bladder lining and reduce pain.
4. Nerve Stimulation Therapies:
Transcutaneous Electrical Nerve Stimulation (TENS): Applying mild electrical pulses to the body may help block pain signals and reduce symptoms.
5. Surgical Interventions:
Bladder Distension: Gently stretching the bladder under anesthesia may provide temporary symptom relief.
Surgical Options: In severe cases unresponsive to other treatments, surgical procedures may be considered to increase bladder capacity or remove the bladder.